The total land area of San Mateo as of the 1976 cadastral survey is approximately 4,825.10 hectares broken-down to fifteen (15) barangays.

The topography of the municipality is characterized by a rolling to mountainous terrain on the eastern side comprising approximately 75.66% or 3,650.67 has. And a flat terrain on the western side bordering Marikina River . The plains cover an approximate area of 1,174.43 has. or 24.34%.

Of the total land area of San Mateo , an approximate area of 1,200 hectares or 25% is devoted to Agriculture. Crop production & value report from the Municipal Agriculture office indicates that 577 hectares have been planted for the year 1997. Of this, Riceland account for 274 hectares (47.49%) while 303 hectares (52.51%) are planted with diversified crops and vegetables.

The Central Business District is strategically located amidst the concentration of settlements.  A major commercial area starts from the vicinity of the public market, bounded by the national road going to Montalban and Daangbakal St . At Barangay Guinangbayan II. This commercial zone is a conglomeration of financial institutions, a public market, restaurants/small eateries, retail stores and the like.

Another area, which may be considered as major commercial area, is within the vicinity of Delos Santos St. corner Gen Luna St. , in Barangay Ampid I.  Other minor commercial areas are located near the Producer’s Market at Barangay Banaba and in the corner of Patiis & Gen Luna St. , in Barangay Malanday.